Relb^tm1.1Jino
Targeted Allele Detail

Summary

• Symbol: Relb^tm1.1Jino
• Name: avian reticuloendotheliosis viral (v-rel) oncogene related B; targeted mutation 1.1, Jun-ichiro Inoue
• MGI ID: MGI:6474232
• Synonyms: RelB^Venus
• Gene: Relb Location: Chr7:19340142-19363352 bp, - strand Genetic Position: Chr7, 9.93 cM
• Alliance: Relb^tm1.1Jino page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:297199
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Epitope tag, Reporter)
• Mutation: Insertion
• Mutation details: A floxed neomycin resistance cassette was inserted upstream of the last coding exon. A Venus reporter gene with a FLAG tag and stop codon were inserted downstream of the coding sequence. Cre-mediated recombination removed the selection cassette. (J:297199)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Relb Mutation: 32 strains or lines available

References

• Original: J:297199 Seki T, et al., Visualization of RelB expression and activation at the single-cell level during dendritic cell maturation in Relb-Venus knock-in mice. J Biochem. 2015;158(6):485-95
• All: 1 reference(s)