Lck^tm1Mal
Targeted Allele Detail

Summary

• Symbol: Lck^tm1Mal
• Name: lck proto-oncogene, Src family tyrosine kinase; targeted mutation 1, Bernard Malissen
• MGI ID: MGI:6468301
• Synonyms: Lck^Y505F
• Gene: Lck Location: Chr4:129442142-129467415 bp, - strand Genetic Position: Chr4, 63.26 cM, cytoband distal
• Alliance: Lck^tm1Mal page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:82809
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Not Specified)
• Mutation: Nucleotide substitutions
• An A-to-T point mutation changes tyrosine codon 505 to phenylalanine (p.Y505F). (J:82809)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Lck Mutation: 96 strains or lines available

References

• Original: J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013
• All: 1 reference(s)