Tnfsf15^tm1.1Geno
Targeted Allele Detail

Summary

• Symbol: Tnfsf15^tm1.1Geno
• Name: tumor necrosis factor (ligand) superfamily, member 15; targeted mutation 1.1, Genoway
• MGI ID: MGI:6466588
• Synonyms: Tnfsf15^flox
• Gene: Tnfsf15 Location: Chr4:63642837-63663296 bp, - strand Genetic Position: Chr4, 34.06 cM
• Alliance: Tnfsf15^tm1.1Geno page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:295074
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Exon 1 is flanked by loxP sites. An frt-flanked neomycin selection cassette was removed via FLP-mediated recombination. (J:295074)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tnfsf15 Mutation: 20 strains or lines available

References

• Original: J:295074 Castellanos JG, et al., Microbiota-Induced TNF-like Ligand 1A Drives Group 3 Innate Lymphoid Cell-Mediated Barrier Protection and Intestinal T Cell Activation during Colitis. Immunity. 2018 Dec 18;49(6):1077-1089.e5
• All: 2 reference(s)