Prdx5^tm1Dsle
Targeted Allele Detail

Summary

• Symbol: Prdx5^tm1Dsle
• Name: peroxiredoxin 5; targeted mutation 1, Dong-Seok Lee
• MGI ID: MGI:6458912
• Gene: Prdx5 Location: Chr19:6884065-6887474 bp, - strand Genetic Position: Chr19, 5.08 cM
• Alliance: Prdx5^tm1Dsle page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:294801
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A neomycin resistance cassette replaced the sequence. (J:294801)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prdx5 Mutation: 18 strains or lines available

References

• Original: J:294801 Kim MH, et al., Peroxiredoxin 5 regulates adipogenesis-attenuating oxidative stress in obese mouse models induced by a high-fat diet. Free Radic Biol Med. 2018 Aug 1;123:27-38
• All: 4 reference(s)