Chrna4^{rs245774393-A}
Spontaneous Allele Detail

Summary

• Symbol: Chrna4^{rs245774393-A}
• Name: cholinergic receptor, nicotinic, alpha polypeptide 4; rs245774393 SNP allele with the A variant
• MGI ID: MGI:6449121
• Gene: Chrna4 Location: Chr2:180664104-180685339 bp, - strand Genetic Position: Chr2, 103.54 cM
• Alliance: Chrna4^{rs245774393-A} page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Spontaneous
• Mutation: Single point mutation
• Mutation details: This A variant of SNP rs245774393, the major variant coding for sserine at codon 6, is found in the following strains: 129P2/OlaHsd, 129P2/OlaHsd, 129S1/SvImJ, 129S5SvEvBrd, A/J, AKR/J, C3H/HeJ, C57BL/6J, C57BL/6NJ, C57BL/10J, C57BR/J, C57L/J, C58/J, CBA/J, CE/J, DBA/1J, DBA/2J, FVB/NJ, I/LnJ, L/J, LP/J, NOD/ShiLtJ, NZB/BiNJ, NZO/HiLtJ, P/J, PL/J, RF/J, SJL/J, SWR/J, and YBR/J. (J:179572)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Chrna4 Mutation: 42 strains or lines available

References

• Original: J:179572 Kim H, et al., The mouse Chrna4 A529T polymorphism alters the ratio of high to low affinity alpha 4 beta 2 nAChRs. Neuropharmacology. 2003 Sep;45(3):345-54
• All: 2 reference(s)