Trio^tm3.1Mzhu
Targeted Allele Detail

Summary

• Symbol: Trio^tm3.1Mzhu
• Name: triple functional domain (PTPRF interacting); targeted mutation 3`.1, Min-Sheng Zhu
• MGI ID: MGI:6449072
• Synonyms: GEF2
• Gene: Trio Location: Chr15:27730737-28025934 bp, - strand Genetic Position: Chr15, 10.4 cM
• Alliance: Trio^tm3.1Mzhu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:291412
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: LoxP sites were inserted to flank exons 43-46. An adjacent frt-flanked neomycin cassette was removed via Flp-mediated recombination. (J:291412)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Trio Mutation: 134 strains or lines available

References

• Original: J:291412 Tao T, et al., Distinct functions of Trio GEF domains in axon outgrowth of cerebellar granule neurons. J Genet Genomics. 2019 Feb;46(2):87-96
• All: 1 reference(s)