Nle1^rs13468707-T
Spontaneous Allele Detail

Summary

• Symbol: Nle1^rs13468707-T
• Name: notchless homolog 1; rs13468707 SNP allele with the T variant
• MGI ID: MGI:6434381
• Synonyms: Nle1^rs2820949-A
• Gene: Nle1 Location: Chr11:82791594-82799237 bp, - strand Genetic Position: Chr11, 50.3 cM
• Alliance: Nle1^rs13468707-T page

Mutation origin

• Strain of Origin: various

Mutation description

• Allele Type: Spontaneous (Not Applicable)
• Mutation: Single point mutation
• Mutation details: This is the major variant of SNP rs13468707 (c.538G>A substitution leading to p.I180V) in exon 6 and codes for the wild-type evolutionary conserved isoleucine. The T variant is found in the 129P2/OlaHsd, 129S1/SvImJ, 129X1/SvJ, 129S5SvEvBrd, BTBR T+ TF/J, C3H/HeJ, CAST/EiJ, CBA/J, LP/J, PWD/PHJ, PWK/PhJ, SPRET/EiJ, and WSB/EiJ strains. This SNP is the equivalent of the well-documented human SNP rs2820949. (J:193532)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nle1 Mutation: 28 strains or lines available

References

• Original: J:193532 Lossie AC, et al., ENU mutagenesis reveals that Notchless homolog 1 (Drosophila) affects Cdkn1a and several members of the Wnt pathway during murine pre-implantation development. BMC Genet. 2012;13:106
• All: 1 reference(s)