Gdf11^em2Awa
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gdf11^em2Awa
• Name: growth differentiation factor 11; endonuclease-mediated mutation 2, Amy J Wagers
• MGI ID: MGI:6434023
• Synonyms: Gdf11-IRES-GFP line #11
• Gene: Gdf11 Location: Chr10:128718164-128727587 bp, - strand Genetic Position: Chr10, 77.18 cM, cytoband D3
• Alliance: Gdf11^em2Awa page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Reporter)
• Mutation: Insertion
• Mutation details: CRISPR/Cas9 technology inserted an IRES-EGFP after the stop codon and at the beginning of the 3'UTR. This allele corresponds to line 11 (J:285380)

Expression

In Mice Carrying this Mutation:

2 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gdf11 Mutation: 11 strains or lines available

References

• Original: J:285380 Goldstein JM, et al., Variation in zygotic CRISPR/Cas9 gene editing outcomes generates novel reporter and deletion alleles at the Gdf11 locus. Sci Rep. 2019 Dec 9;9(1):18613
• All: 1 reference(s)