Gabra5^tm2.1Twr
Targeted Allele Detail

Summary

• Symbol: Gabra5^tm2.1Twr
• Name: gamma-aminobutyric acid type A receptor subunit alpha 5; targeted mutation 2.1, Thomas W Rosahl
• MGI ID: MGI:6431808
• Synonyms: Gabra5^{tm1.1(H105R)Twr}
• Gene: Gabra5 Location: Chr7:57057420-57159807 bp, - strand Genetic Position: Chr7, 33.52 cM
• Alliance: Gabra5^tm2.1Twr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:147112
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Not Specified)
• Mutations: Insertion, Nucleotide substitutions
• Mutation details: The H105R point mutation was introduced into Gabra5 exon 4. The neomycin resistance cassette, which is flanked by loxP sites, was introduced into intron 3. Cre-mediated recombination removed the selection cassette. (J:147112)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gabra5 Mutation: 30 strains or lines available

References

• Original: J:147112 Taconic, Information obtained from Taconic website. MGI Direct Data Submission. 2006-2017
• All: 1 reference(s)