Mrc1^tm1.2Bpip
Targeted Allele Detail

Summary

• Symbol: Mrc1^tm1.2Bpip
• Name: mannose receptor, C type 1; targeted mutation 1.2 Bernard Pipy
• MGI ID: MGI:6416810
• Synonyms: Mrc1^-
• Gene: Mrc1 Location: Chr2:14234225-14336834 bp, + strand Genetic Position: Chr2, 10.46 cM
• Alliance: Mrc1^tm1.2Bpip page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:203147
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: A region of the gene was deleted following Cre-mediated deletion of loxP sites in the germline (details not specified). (J:203147)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mrc1 Mutation: 88 strains or lines available

References

• Original: J:203147 Lefevre L, et al., The C-type lectin receptors dectin-1, MR, and SIGNR3 contribute both positively and negatively to the macrophage response to Leishmania infantum. Immunity. 2013 May 23;38(5):1038-49
• All: 4 reference(s)