Slc38a4^em#Smtb
Endonuclease-mediated Allele Detail

Summary

• Symbol: Slc38a4^em#Smtb
• Name: solute carrier family 38, member 4; endonuclease-mediated mutation, Shogo Matoba
• MGI ID: MGI:6403492
• Gene: Slc38a4 Location: Chr15:96892701-96953837 bp, - strand Genetic Position: Chr15, 52.77 cM
• Alliance: Slc38a4^em#Smtb page

Mutation origin

• Strain of Origin: C57BL/6NSlc

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR-targeting of the first 10 exons created 3 deletion lines. The pound symbol (#) is used to represent a pool of two deletion lines: #12-B 23146bp del 95997025 to 97020173, and #12-C 23075bp del 96997028 to 97020173 (mm10). (J:280426)

Expression

In Mice Carrying this Mutation:	72 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc38a4 Mutation: 116 strains or lines available

References

• Original: J:280426 Matoba S, et al., Paternal knockout of Slc38a4/SNAT4 causes placental hypoplasia associated with intrauterine growth restriction in mice. Proc Natl Acad Sci U S A. 2019 Oct 15;116(42):21047-21053
• All: 3 reference(s)