Mip^em2(IMPC)H
Endonuclease-mediated Allele Detail

Summary

• Symbol: Mip^em2(IMPC)H
• Name: major intrinsic protein of lens fiber; endonuclease-mediated mutation 2, Harwell
• MGI ID: MGI:6399919
• Gene: Mip Location: Chr10:128061707-128067681 bp, + strand Genetic Position: Chr10, 76.49 cM, cytoband D1
• Alliance: Mip^em2(IMPC)H page
• IMPC: Mip gene page

Mutation origin

• Strain of Origin: C57BL/6NTac
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: This allele was generated at Medical Research Council Harwell using Cas9 and guides with spacer sequences AGTGACCGCAGGGTTGACAT, TCTTTGCTACATACGACGAG, TGGAGCCCATGTCAACCCTG, and TTGCTACATACGACGAGAGG. This resulted in insertions of 1 bp (location: chr10:128061950; GRCm39), 4 bp (location: chr10:128063005; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mip Mutation: 31 strains or lines available

References

• Original: J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023
• All: 2 reference(s)