Slc17a8em1(icre/ERT2)Zyliu
Endonuclease-mediated Allele Detail
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Symbol: |
Slc17a8em1(icre/ERT2)Zyliu |
Name: |
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8; endonuclease-mediated mutation 1, Zhiyong Liu |
MGI ID: |
MGI:6384614 |
Synonyms: |
vGlut3-P2A-iCreER |
Gene: |
Slc17a8 Location: Chr10:89409882-89457111 bp, - strand Genetic Position: Chr10, 44.99 cM
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Alliance: |
Slc17a8em1(icre/ERT2)Zyliu page
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Allele Type: |
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Endonuclease-mediated (Inducible, Recombinase) |
Inducer: |
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tamoxifen |
Mutation: |
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Insertion
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Slc17a8em1(icre/ERT2)Zyliu expression driven by
1 gene
Knock-in expression driven by:
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Mutation details: A plasmid encoding a guide RNA and PAM sequence TGG was designed to introduce a P2A peptide fused to an icre/ERT2 cassette into exon 12, immediately before the stop codon, of the solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8 (Slc17a8) gene. Guide RNA and the cas9 nuclease were introduced into the cytoplasm of C57BL/6N-derived fertilized eggs with well recognized pronuclei.
(J:282727)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Slc17a8
(mouse)
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Original: |
J:282727 Li C, et al., Characterizing a novel vGlut3-P2A-iCreER knockin mouse strain in cochlea. Hear Res. 2018 Jul;364:12-24 |
All: |
5 reference(s) |
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