Rce1^tm1Visu
Targeted Allele Detail

Summary

• Symbol: Rce1^tm1Visu
• Name: Ras converting CAAX endopeptidase 1; targeted mutation 1, Visvanathan Ramamurthy
• MGI ID: MGI:6382983
• Synonyms: Rce1^null
• Gene: Rce1 Location: Chr19:4672619-4675669 bp, - strand Genetic Position: Chr19, 4.07 cM
• Alliance: Rce1^tm1Visu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:171900
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: This allele was created through cre-mediated recombination by crossing mice with floxed allele Rce1^tm2Kim with mice carying the Tmem163^{Tg(ACTB-cre)2Mrt} allele. (J:171900)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rce1 Mutation: 14 strains or lines available

References

• Original: J:171900 Christiansen JR, et al., RAS-converting enzyme 1-mediated endoproteolysis is required for trafficking of rod phosphodiesterase 6 to photoreceptor outer segments. Proc Natl Acad Sci U S A. 2011 May 24;108(21):8862-6
• All: 1 reference(s)