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Tmem163Tg(ACTB-cre)2Mrt
Transgenic Allele Detail
Nomenclature
Symbol: Tmem163Tg(ACTB-cre)2Mrt
Name: transmembrane protein 163; transgene insertion 2, Gail R Martin
MGI ID: MGI:2176050
Synonyms: A-cre, ACTB-cre, Act-Cre, actin-cre, beta-actin-cre, beta-actin-Cre, beta-actin:Cre, beta-actin::Cre, creactin, TgN(ACTB-cre)2Mrt
Gene: Tmem163  Location: Chr1:127490342-127679621 bp, - strand  Genetic Position: Chr1, 55.77 cM, cytoband E3
Reduced body size in Raph1tm1.1Makr/Raph1tm1.1Makr Tmem163Tg(ACTB-cre)2Mrt/0 mice

Show the 2 phenotype image(s) involving this allele.

Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThis transgene expresses Cre recombinase under the control of a human beta-actin promoter, which is active in all embryonic cells at or before the blastocyst stage. Line number 2 contains a single copy of the transgene inserted into intron 4 of Tmem163 (chr1:129,442,346; NCBI37/mm9) with three intronic deletions of 2.2, 7.3 and 3.2 kb, respectively, surrounding the transgene integration site. (J:46833, J:240920)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: ACTB     Summary of all recombinase alleles driven by ACTB.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 64 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Tmem163 Mutation:  4 strains or lines available
References
Original:  J:46833 Lewandoski M, et al., Analysis of Fgf8 gene function in vertebrate development. Cold Spring Harb Symp Quant Biol. 1997;62:159-68
All:  290 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/18/2019
MGI 6.14
The Jackson Laboratory