Rarres2^tm1Cya
Targeted Allele Detail

Summary

• Symbol: Rarres2^tm1Cya
• Name: retinoic acid receptor responder (tazarotene induced) 2; targeted mutation 1, Cyagen Biosciences
• MGI ID: MGI:6364881
• Synonyms: Rarres2^tm1Cgen
• Gene: Rarres2 Location: Chr6:48546630-48549723 bp, - strand Genetic Position: Chr6, 23.55 cM
• Alliance: Rarres2^tm1Cya page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:278613
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exons 1-3 were replaced with a neomycin resistance cassette. (J:278613)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rarres2 Mutation: 12 strains or lines available

References

• Original: J:278613 Lin Y, et al., Chemerin has a protective role in hepatocellular carcinoma by inhibiting the expression of IL-6 and GM-CSF and MDSC accumulation. Oncogene. 2017 Jun 22;36(25):3599-3608
• All: 5 reference(s)