Npy2r^em3978Tac
Endonuclease-mediated Allele Detail

Summary

• Symbol: Npy2r^em3978Tac
• Name: neuropeptide Y receptor Y2; endonuclease-mediated mutation 3978, Taconic
• MGI ID: MGI:6363411
• Synonyms: Y2R KO
• Gene: Npy2r Location: Chr3:82445690-82455391 bp, - strand Genetic Position: Chr3, 36.49 cM
• Alliance: Npy2r^em3978Tac page

Mutation origin

• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Cas9-mediated gene editing resulted in complete excision of the open reading frame, part of the 5' untranslated region and all of the 3' untranslated region. (J:279552)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Npy2r Mutation: 31 strains or lines available

References

• Original: J:279552 Boland B, et al., The PYY/Y2R-Deficient Mouse Responds Normally to High-Fat Diet and Gastric Bypass Surgery. Nutrients. 2019 Mar 10;11(3)
• All: 4 reference(s)