Dusp26^em1Jhxia
Endonuclease-mediated Allele Detail

Summary

• Symbol: Dusp26^em1Jhxia
• Name: dual specificity phosphatase 26; endonuclease-mediated mutation 1, Jiahong Xia
• MGI ID: MGI:6361751
• Synonyms: DUSP26 flox
• Gene: Dusp26 Location: Chr8:31579555-31587074 bp, + strand Genetic Position: Chr8, 17.93 cM, cytoband A3
• Alliance: Dusp26^em1Jhxia page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• CRISPR-targeting was used to floxed exon 4. (J:279111)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dusp26 Mutation: 18 strains or lines available

References

• Original: J:279111 Ye P, et al., Dual-Specificity Phosphatase 26 Protects Against Nonalcoholic Fatty Liver Disease in Mice Through Transforming Growth Factor Beta-Activated Kinase 1 Suppression. Hepatology. 2019 May;69(5):1946-1964
• All: 1 reference(s)