Ifngas1^tm1.1Oshea
Targeted Allele Detail

Summary

• Symbol: Ifngas1^tm1.1Oshea
• Name: Ifng antisense RNA 1; targeted mutation 1.1, John O'Shea
• MGI ID: MGI:6359815
• Gene: Ifngas1 Location: Chr10:118337940-118392430 bp, - strand Genetic Position: Chr10, Syntenic
• Alliance: Ifngas1^tm1.1Oshea page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:283672
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Intragenic deletion
• Mutation details: The targeting vector is designed to replace exon 1 and intron 1 of the gene with an enhanced green fluorescent protein sequence (EGFP) and an FRT-flanked puromycin resistance (puro) cassette. Flp-mediated recombination removed the FRT-flanked puro cassette. (J:283672)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ifngas1 Mutation: 1 strain or line available

References

• Original: J:283672 Petermann F, et al., The Magnitude of IFN-gamma Responses Is Fine-Tuned by DNA Architecture and the Non-coding Transcript of Ifng-as1. Mol Cell. 2019 Sep 19;75(6):1229-1242.e5
• All: 1 reference(s)