Amfr^tm1.2Blsg
Targeted Allele Detail

Summary

• Symbol: Amfr^tm1.2Blsg
• Name: autocrine motility factor receptor; targeted mutation 1.2, Bao-Liang Song
• MGI ID: MGI:6358040
• Synonyms: gp78^-
• Gene: Amfr Location: Chr8:94698216-94739301 bp, - strand Genetic Position: Chr8, 45.96 cM
• Alliance: Amfr^tm1.2Blsg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:247052
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S1/SvImJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Exons 5-8 were deleted via Cre-mediated recombination of flanking loxP sites in the germline. (J:270119)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Amfr Mutation: 43 strains or lines available

References

• Original: J:247052 Wang YJ, et al., Cholesterol and fatty acids regulate cysteine ubiquitylation of ACAT2 through competitive oxidation. Nat Cell Biol. 2017 Jul;19(7):808-819
• All: 4 reference(s)