Mettl14^em1Chhe
Endonuclease-mediated Allele Detail

Summary

• Symbol: Mettl14^em1Chhe
• Name: methyltransferase 14, N6-adenosine-methyltransferase subunit; endonuclease-mediated mutation 1, Chuan He
• MGI ID: MGI:6356357
• Synonyms: Mettl14^flox
• Gene: Mettl14 Location: Chr3:123161944-123179639 bp, - strand Genetic Position: Chr3, 53.96 cM
• Alliance: Mettl14^em1Chhe page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Exon 2 was flanked by loxP sites. (J:250428)

Expression

In Mice Carrying this Mutation:	2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mettl14 Mutation: 36 strains or lines available

References

• Original: J:250428 Lin Z, et al., Mettl3-/Mettl14-mediated mRNA N(6)-methyladenosine modulates murine spermatogenesis. Cell Res. 2017 Oct;27(10):1216-1230
• All: 6 reference(s)