Tardbp^Rgsc2223
Chemically induced Allele Detail

Summary

• Symbol: Tardbp^Rgsc2223
• Name: TAR DNA binding protein; Riken Genomic Sciences Center 2223
• MGI ID: MGI:6355456
• Synonyms: GD000110, LCDmut, M323K
• Gene: Tardbp Location: Chr4:148696839-148711476 bp, - strand Genetic Position: Chr4, 78.77 cM
• Alliance: Tardbp^Rgsc2223 page

Mutation origin

• Strain of Origin: C57BL/6JJcl

Mutation description

• Allele Type: Chemically induced (ENU) (Modified isoform(s))
• Mutation: Single point mutation
• Mutation details: The ENU-induced mutation is a c.968T>A substitution that changes methionine codon 323 to a lysine codon (p.Met323Lys, p.M323K). The mutation is located in the low complexity domain (LCD) of the encoded peptide. (J:101000)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 6 strains available Cell Lines: 0 lines available
• Carrying any Tardbp Mutation: 60 strains or lines available

References

• Original: J:101000 Sakuraba Y, et al., Molecular characterization of ENU mouse mutagenesis and archives. Biochem Biophys Res Commun. 2005 Oct 21;336(2):609-16
• All: 5 reference(s)