Ncoa4^tm1.1Jdom
Targeted Allele Detail

Summary

• Symbol: Ncoa4^tm1.1Jdom
• Name: nuclear receptor coactivator 4; targeted mutation 1.1, Joseph Mancias
• MGI ID: MGI:6306108
• Synonyms: Ncoa^fl
• Gene: Ncoa4 Location: Chr14:31881884-31901210 bp, + strand Genetic Position: Chr14, 19.4 cM, cytoband B
• Alliance: Ncoa4^tm1.1Jdom page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:274988
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: The targeting vector contains an FRT-flanked Neo selection cassette inserted downstream of exon 6 and another loxP site inserted upstream of exon 2. Flp-mediated recombination removed the FRT-flanked neo cassette leaving exons 2 through 6 floxed. (J:274988)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ncoa4 Mutation: 76 strains or lines available

References

• Original: J:274988 Santana-Codina N, et al., NCOA4 maintains murine erythropoiesis via cell autonomous and non-autonomous mechanisms. Haematologica. 2019 Jan 10
• All: 2 reference(s)