Oip5os1^tm1.2Dpbl
Targeted Allele Detail

Summary

• Symbol: Oip5os1^tm1.2Dpbl
• Name: Opa interacting protein 5, opposite strand 1; targeted mutation 1.2, David P Bartel
• MGI ID: MGI:6295970
• Gene: Oip5os1 Location: Chr2:119424777-119431227 bp, + strand Genetic Position: Chr2, 59.97 cM
• Alliance: Oip5os1^tm1.2Dpbl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:265657
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S6/SvEvTac x C57BL/6J

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 3. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted in exon 3 downstream of the site for induction of Mir 7 degradation. Flp-mediated recombination removed the selection cassette. Cre-mediated recombination removed the coding sequence of exon 3 up to and including the Mir site. (J:265657)

Expression

In Mice Carrying this Mutation:

100 assay results 3 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Oip5os1 Mutation: 5 strains or lines available

References

• Original: J:265657 Kleaveland B, et al., A Network of Noncoding Regulatory RNAs Acts in the Mammalian Brain. Cell. 2018 Jul 12;174(2):350-362.e17
• All: 1 reference(s)