Rr171^em1Mhk
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rr171^em1Mhk
• Name: regulatory region 171; endonuclease-mediated mutation 1, Marh H Kaplan
• MGI ID: MGI:6287642
• Synonyms: Il9^deltaCNS25, Il9^em1Mhk
• Gene: Rr171 Location: Chr13:56654647-56655370 bp Genetic Position: Chr13, Syntenic
• Alliance: Rr171^em1Mhk page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Modified regulatory region)
• Mutation: Intragenic deletion
• Mutation details: CRISPR-targeting deleted the sequence containing Il9 upstream enhancer conserved non-coding sequence 25 (CNS-25), located 25 kb upstream of the gene. (J:268610)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rr171 Mutation: 0 strains or lines available

References

• Original: J:268610 Koh B, et al., A conserved enhancer regulates Il9 expression in multiple lineages. Nat Commun. 2018 Nov 15;9(1):4803
• All: 3 reference(s)