Dars1^{em1(IMPC)Wtsi}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Dars1^{em1(IMPC)Wtsi}
• Name: aspartyl-tRNA synthetase 1; endonuclease-mediated mutation 1, Wellcome Trust Sanger Institute
• MGI ID: MGI:6281944
• Gene: Dars1 Location: Chr1:128291444-128345105 bp, - strand Genetic Position: Chr1, 55.8 cM
• Alliance: Dars1^{em1(IMPC)Wtsi} page
• IMPC: Dars1 gene page

Mutation origin

• Strain of Origin: C57BL/6N
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele from IMPC was generated at Welcome Trust Sanger Institute by injecting CAS9 RNA and 4 guide sequences CCTTACGGGTCAAATGCAGGTTA, CCATTCTTTAACACGGGAGACTG, AACGTTAATAATCTCATTAGAGG, TAGAACTATTAAGACCATAAAGG, which resulted in a Exon Deletion. (J:265051)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dars1 Mutation: 69 strains or lines available

References

• Original: J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023
• All: 1 reference(s)