Del(15Rr38-Rr313939)7Fsp
Transposon induced Allele Detail

Summary

• Symbol: Del(15Rr38-Rr313939)7Fsp
• Name: deletion, Chr 15, Francois Spitz 7
• MGI ID: MGI:6281724
• Synonyms: Del(15-TgTn(sb-SBlac)15.184347Fsp-TgTn(sb-SBlac)15.179039Fsp)1Fsp, Del7Fsp, del(8-17), Df(184347-179039)
• Gene: Del(15Rr38-Rr313939)7Fsp Location: unknown Genetic Position: Chr15, Syntenic

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Transposon induced (Conditional ready, Modified regulatory region, Reporter)
• Mutations: Insertion, Intergenic deletion
• Del(15Rr38-Rr313939)7Fsp involves 22 genes/genome features (Rr332, Rr331, Rr38 ...) View all
• Mutation details: Cre-mediated inter-chromosomal recombination between Tn(sb-SBlac)15.184347Fsp at chr15:62708842-62708843 (GRCm39) and Tn(sb-SBlac)15.179039Fsp at chr15:63590844-63590845 deleted approximately 882 kb and leaves one intact copy of the transposon cassette (in forward orientation) at the deletion junction. The transposon consists of a Sleeping Beauty transposon inverted repeat, loxP site, human beta-globin HBB minimal promoter, the lacZ beta-galactosidase reporter gene, SV40 poly(A) signal sequence, and a Sleeping Beauty transposon direct repeat. The deleted sequence is part of the Myc topologically associating domain (TAD) and contains Myc enhancers Rr38, Rr334, Rr316124, Rr313933, Rr331, Rr307328, Rr332, Rr307330, Rr333 and Rr313939. (J:180121)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Del(15Rr38-Rr313939)7Fsp Mutation: 0 strains or lines available

References

• Original: J:180121 Ruf S, et al., Large-scale analysis of the regulatory architecture of the mouse genome with a transposon-associated sensor. Nat Genet. 2011 Apr;43(4):379-86
• All: 3 reference(s)