Del(14Lrit1-Lrit2)1Tfur
Targeted Allele Detail

Summary

• Symbol: Del(14Lrit1-Lrit2)1Tfur
• Name: deletion, Chr 14, Takahisa Furukawa 1
• MGI ID: MGI:6281358
• Synonyms: Lrit1/2 DKO, Lrit1/Lrit2^tm1Tfur
• Gene: Del(14Lrit1-Lrit2)1Tfur Location: unknown Genetic Position: Chr14, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:271244
• Parent Cell Line: JM8A3 (ES Cell)
• Strain of Origin: C57BL/6N-A^tm1Brd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intergenic deletion, Intragenic deletion
• Del(14Lrit1-Lrit2)1Tfur involves 2 genes/genome features (Lrit1, Lrit2) View all
• Mutation details: The genomic region containing Lrit1 exon 2-4 and Lrit2 exon 1-2 was replaced with a FRT-flanked PGK-neomycin cassette and a loxP site. RT-PCR confirmed absence of Lrit1 and Lrit2 transcripts in the retina. (J:271244)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Del(14Lrit1-Lrit2)1Tfur Mutation: 0 strains or lines available

References

• Original: J:271244 Ueno A, et al., Lrit1, a Retinal Transmembrane Protein, Regulates Selective Synapse Formation in Cone Photoreceptor Cells and Visual Acuity. Cell Rep. 2018 Mar 27;22(13):3548-3561
• All: 1 reference(s)