Map3k5^tm3.1Hijo
Targeted Allele Detail

Summary

• Symbol: Map3k5^tm3.1Hijo
• Name: mitogen-activated protein kinase kinase kinase 5; targeted mutation 3.1, Hidenori Ichijo
• MGI ID: MGI:6273513
• Synonyms: ASK1^flox
• Gene: Map3k5 Location: Chr10:19810218-20018499 bp, + strand Genetic Position: Chr10, 9.35 cM
• Alliance: Map3k5^tm3.1Hijo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:236904
• Parent Cell Line: RENKA (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was placed 5' to exon 15 and an frt-flanked neomycin selection cassette followed by a second loxP site was inserted 3' to exon 15. The neomycin selection cassette was removed by FLP-mediated recombination. (J:236904)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Map3k5 Mutation: 62 strains or lines available

References

• Original: J:236904 Hattori K, et al., ASK1 signalling regulates brown and beige adipocyte function. Nat Commun. 2016 Apr 05;7:11158
• All: 3 reference(s)