Kcnk18^tm1.1Yost
Targeted Allele Detail

Summary

• Symbol: Kcnk18^tm1.1Yost
• Name: potassium channel, subfamily K, member 18; targeted mutation 1.1, C Spencer Yost
• MGI ID: MGI:6267475
• Gene: Kcnk18 Location: Chr19:59208080-59225802 bp, + strand Genetic Position: Chr19, 54.63 cM
• Alliance: Kcnk18^tm1.1Yost page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:266791
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A floxed neomycin resistant cassette replaced exon III, which encodes most of the channel subunit, and was removed by cre-mediated recombination. (J:266791)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kcnk18 Mutation: 18 strains or lines available

References

• Original: J:266791 Chae YJ, et al., Discrete change in volatile anesthetic sensitivity in mice with inactivated tandem pore potassium ion channel TRESK. Anesthesiology. 2010 Dec;113(6):1326-37
• All: 1 reference(s)