Btbd7^tm1.1Kmy
Targeted Allele Detail

Summary

• Symbol: Btbd7^tm1.1Kmy
• Name: BTB domain containing 7; targeted mutation 1.1, Kenneth Yamada
• MGI ID: MGI:6259681
• Gene: Btbd7 Location: Chr12:102747056-102844730 bp, - strand Genetic Position: Chr12, 52.25 cM
• Alliance: Btbd7^tm1.1Kmy page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:241996
• Parent Cell Line: W4 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: A loxP site was introduced to intron 2 and an FRT-PGK-neo-FRT cassette and loxP site were placed in intron 4 of the gene. Cre mediated recombination removed exons 3 and 4 and the neo cassette. (J:241996)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Btbd7 Mutation: 42 strains or lines available

References

• Original: J:241996 Daley WP, et al., Btbd7 is essential for region-specific epithelial cell dynamics and branching morphogenesis in vivo. [retracted]. Development. 2017 Jun 15;144(12):2200-2211
• All: 1 reference(s)