Mir21a^tm1Eno
Targeted Allele Detail

Summary

• Symbol: Mir21a^tm1Eno
• Name: microRNA 21a; targeted mutation 1, Eric N Olson
• MGI ID: MGI:6201556
• Synonyms: miR-21^fl
• Gene: Mir21a Location: Chr11:86474893-86474984 bp, - strand Genetic Position: Chr11, 51.82 cM
• Alliance: Mir21a^tm1Eno page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:166911
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

Allele Type: Targeted (Conditional ready) Mutation: Insertion Mutation details: A loxP site was inserted upstream of the coding sequence, and an FRT-flanked neo cassette with a 3' loxP site was inserted downstream of the coding sequence. (J:166911)

Generation of the Mir21a^tm1Eno allele

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mir21a Mutation: 12 strains or lines available

References

• Original: J:166911 Patrick DM, et al., Stress-dependent cardiac remodeling occurs in the absence of microRNA-21 in mice. J Clin Invest. 2010 Nov 1;120(11):3912-6
• All: 8 reference(s)