Myh9^{tm10.1(Myh14/EGFP)Rsad}
Targeted Allele Detail

Summary

• Symbol: Myh9^{tm10.1(Myh14/EGFP)Rsad}
• Name: myosin, heavy polypeptide 9, non-muscle; targeted mutation 10.1, Robert S Adelstein
• MGI ID: MGI:6159153
• Gene: Myh9 Location: Chr15:77644788-77726315 bp, - strand Genetic Position: Chr15, 36.81 cM
• Alliance: Myh9^{tm10.1(Myh14/EGFP)Rsad} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:94077
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Mutation details: A Myh14 cDNA encoding the NMHCII-C1 isoform of mouse non-muscle heavy chain 2C, which includes the 8-amino-acid C1 insertion in loop 1 (from an alternatively spliced exon), fused at its 3' end to the coding sequence for enhanced green fluorescent protein and followed by a loxP-flanked Pgk-neo cassette, was inserted into exon 2 of the NMHCII-A-encoding Myh9 locus immediately downstream of the translation-initiating ATG codon. The selection cassette subsequently was deleted by Cre recombinase. (J:94077)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Myh9 Mutation: 221 strains or lines available

References

• Original: J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015
• All: 1 reference(s)