Ppm1b^tm1.2Tamu
Targeted Allele Detail

Summary

• Symbol: Ppm1b^tm1.2Tamu
• Name: protein phosphatase 1B, magnesium dependent, beta isoform; targeted mutation 1.2, Shinri Tamura
• MGI ID: MGI:6157762
• Gene: Ppm1b Location: Chr17:85264169-85331419 bp, + strand Genetic Position: Chr17, 55.13 cM, cytoband E4-E5
• Alliance: Ppm1b^tm1.2Tamu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:121900
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A floxed PGK-neo selection cassette was inserted into intron 3 and a third loxP site was inserted into intron 4. Cre-mediated recombination removed the PGK-neo selection cassette, leaving loxP sites flanking exon 4. (J:121900)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ppm1b Mutation: 40 strains or lines available

References

• Original: J:121900 Sasaki M, et al., Disruption of the mouse protein Ser/Thr phosphatase 2Cbeta gene leads to early pre-implantation lethality. Mech Dev. 2007 Jul;124(6):489-99
• All: 1 reference(s)