Tg(IgkV3-2*01)L16Fosm
Transgene Detail

Summary

• Symbol: Tg(IgkV3-2*01)L16Fosm
• Name: transgene insertion L16, Mary Foster
• MGI ID: MGI:6156582
• Synonyms: IGKV3 LC Tg, mLCV3-Tg
• Transgene: Tg(IgkV3-2*01)L16Fosm Location: unknown
• Alliance: Tg(IgkV3-2*01)L16Fosm page

Transgene origin

• Strain of Origin: C57BL/6NHsd

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(IgkV3-2*01)L16Fosm expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Igk (MGI:96494)

• Mutation details: The transgene comprises the rearranged IGKV3-2*01 (formerly Vk21C)/Jk2 immunoglobulin kappa light chain from a hybridoma cell line. It encodes the light chain of antibodies generated in C57BL/6 mice against the antigenic NC1 domain from collagen type IV, alpha 3 (anti-alpha3(IV)NC1). (J:140740, J:261505)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:261505 Clark AG, et al., A murine Ig light chain transgene reveals IGKV3 gene contributions to anti-collagen types IV and II specificities. Mol Immunol. 2017 Nov;91:49-56
• All: 2 reference(s)