Grik2^tm1.1Cont
Targeted Allele Detail

Summary

• Symbol: Grik2^tm1.1Cont
• Name: glutamate receptor, ionotropic, kainate 2 (beta 2); targeted mutation 1.1, Anis Contractor
• MGI ID: MGI:6154884
• Synonyms: Grik2f
• Gene: Grik2 Location: Chr10:48970929-49664862 bp, - strand Genetic Position: Chr10, 24.87 cM
• Alliance: Grik2^tm1.1Cont page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:261202
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Exon 13 was floxed and a floxed neo cassette was inserted via homologous recombination. Cre mediated recombination removed the neo cassette leaving exon 13 floxed. (J:261202)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Grik2 Mutation: 66 strains or lines available

References

• Original: J:261202 Marshall JJ, et al., Kainate Receptors Inhibit Glutamate Release Via Mobilization of Endocannabinoids in Striatal Direct Pathway Spiny Projection Neurons. J Neurosci. 2018 Apr 18;38(16):3901-3910
• All: 3 reference(s)