Itm2a^{em1(IMPC)Wtsi}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Itm2a^{em1(IMPC)Wtsi}
• Name: integral membrane protein 2A; endonuclease-mediated mutation 1, Wellcome Trust Sanger Institute
• MGI ID: MGI:6153374
• Gene: Itm2a Location: ChrX:106440801-106446966 bp, - strand Genetic Position: ChrX, 47.52 cM, cytoband A2-A3
• Alliance: Itm2a^{em1(IMPC)Wtsi} page
• IMPC: Itm2a gene page

Mutation origin

• Strain of Origin: C57BL/6N
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at Wellcome Sanger Institute using Cas9 and guides with spacer sequences AATTGGACAATCGCTTGCAG, CGTTGAAACCAAGATCTGTC, GTGTGCTGTGCCAAAATAGA, and TTAATCAGTGTTCTGTGTTC that targeted exon(s) ENSMUSE00000207556.6 ENSMUSE00000207557.2. This resulted in deletion(s) of 801 bp (location: ChrX:106441332-106442132; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Itm2a Mutation: 7 strains or lines available

References

• Original: J:237616 MGI and IMPC, MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). MGI Direct Data Submission. 2017-8
• All: 2 reference(s)