Pcdha^em1Jrs
Endonuclease-mediated Allele Detail

Summary

• Symbol: Pcdha^em1Jrs
• Name: protocadherin alpha cluster; endonuclease-mediated mutation 1, Joshua R Sanes
• MGI ID: MGI:6147680
• Synonyms: ag^f-1
• Gene: Pcdha Location: unknown Genetic Position: Chr18, Syntenic

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/cas9 induced a 133 bp deletion in exon 1 spanning the exon - intron splice site in ES cells carrying the Pcdhg^tm2Xzw conditional ready allele. The deletion and floxed alleles are on the same chromosome. (J:258146)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pcdha Mutation: 52 strains or lines available

References

• Original: J:258146 Ing-Esteves S, et al., Combinatorial Effects of Alpha- and Gamma-Protocadherins on Neuronal Survival and Dendritic Self-Avoidance. J Neurosci. 2018 Mar 14;38(11):2713-2729
• All: 1 reference(s)