Grik2^tm1.1Ksak
Targeted Allele Detail

Summary

• Symbol: Grik2^tm1.1Ksak
• Name: glutamate receptor, ionotropic, kainate 2 (beta 2); targeted mutation 1.1, Kenji Sakimura
• MGI ID: MGI:6117330
• Synonyms: Grik2^tm1.1Yuza
• Gene: Grik2 Location: Chr10:48970929-49664862 bp, - strand Genetic Position: Chr10, 24.87 cM
• Alliance: Grik2^tm1.1Ksak page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:239574
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A PGK/Neo cassette flanked by FRT sites and a loxP sequence were inserted at 311 bp upstream of exon 14 and the second loxP sequence was placed at 241 bp downstream of exon 14. Cre-mediated recombination removed the PGK/Neo cassette and exon 14. (J:239574)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Grik2 Mutation: 63 strains or lines available

References

• Original: J:239574 Matsuda K, et al., Transsynaptic Modulation of Kainate Receptor Functions by C1q-like Proteins. Neuron. 2016 May 18;90(4):752-67
• All: 3 reference(s)