Lipe^tm2Gam
Targeted Allele Detail

Summary

• Symbol: Lipe^tm2Gam
• Name: lipase, hormone sensitive; targeted mutation 2, Grant A Mitchell
• MGI ID: MGI:6111341
• Synonyms: Lipe^flox
• Gene: Lipe Location: Chr7:25078952-25097911 bp, - strand Genetic Position: Chr7, 13.78 cM, cytoband A3
• Alliance: Lipe^tm2Gam page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:243296
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• LoxP sites were inserted to flank exon 1. (J:243296)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lipe Mutation: 37 strains or lines available

References

• Original: J:243296 Wu JW, et al., Epistatic interaction between the lipase-encoding genes Pnpla2 and Lipe causes liposarcoma in mice. PLoS Genet. 2017 May;13(5):e1006716
• All: 2 reference(s)