Klb^em1Djm
Endonuclease-mediated Allele Detail

Summary

• Symbol: Klb^em1Djm
• Name: klotho beta; endonuclease-mediated mutation 1, David J Mangelsdorf
• MGI ID: MGI:6109964
• Synonyms: beta-Klotho-Tdtomato, KLB-T
• Gene: Klb Location: Chr5:65505657-65541350 bp, + strand Genetic Position: Chr5, 33.64 cM
• Alliance: Klb^em1Djm page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Reporter)
• Mutation: Insertion
• Mutation details: The coding region of the Tdtomato gene was fused in-frame to the 3 end of the last coding exon (exon 5) of the gene. (J:251865)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Klb Mutation: 59 strains or lines available

References

• Original: J:251865 Coate KC, et al., FGF21 Is an Exocrine Pancreas Secretagogue. Cell Metab. 2017 Feb 7;25(2):472-480
• All: 3 reference(s)