Arrb1^tm1.1Rjl
Targeted Allele Detail

Summary

• Symbol: Arrb1^tm1.1Rjl
• Name: arrestin, beta 1; targeted mutation 1.1, Robert J Lefkowitz
• MGI ID: MGI:5927427
• Synonyms: fl barr1
• Gene: Arrb1 Location: Chr7:99184673-99255978 bp, + strand Genetic Position: Chr7, 54.09 cM
• Alliance: Arrb1^tm1.1Rjl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:280847
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6 x 129

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• A loxP site was inserted into intron 1 and a second loxP site into intron 2. (J:280847)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Arrb1 Mutation: 30 strains or lines available

References

• Original: J:280847 Kim J, et al., beta-arrestin 1 regulates beta2-adrenergic receptor-mediated skeletal muscle hypertrophy and contractility. Skelet Muscle. 2018 Dec 27;8(1):39
• All: 10 reference(s)