Htr1b^tm1Pggd
Targeted Allele Detail

Summary

• Symbol: Htr1b^tm1Pggd
• Name: 5-hydroxytryptamine (serotonin) receptor 1B; targeted mutation 1, Paul Greengard
• MGI ID: MGI:5912385
• Synonyms: htr1b^flox
• Gene: Htr1b Location: Chr9:81510344-81515881 bp, - strand Genetic Position: Chr9, 44.61 cM
• Alliance: Htr1b^tm1Pggd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:229939
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: The promoter and exon were floxed and a human growth hormone polyadenylation signal was inserted 3' of the gene. (J:229939)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Htr1b Mutation: 26 strains or lines available

References

• Original: J:229939 Virk MS, et al., Opposing roles for serotonin in cholinergic neurons of the ventral and dorsal striatum. Proc Natl Acad Sci U S A. 2016 Jan 19;113(3):734-9
• All: 3 reference(s)