Bmp6^tm1.1Lex
Targeted Allele Detail

Summary

• Symbol: Bmp6^tm1.1Lex
• Name: bone morphogenetic protein 6; targeted mutation 1.1, Lexicon Genetics
• MGI ID: MGI:5910409
• Synonyms: Bmp6^-
• Gene: Bmp6 Location: Chr13:38529098-38684283 bp, + strand Genetic Position: Chr13, 18.15 cM
• Alliance: Bmp6^tm1.1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:238919
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Coding exons 5, 6, and 7 were deleted via Cre-mediated recombination of loxP sites. (J:238919)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bmp6 Mutation: 32 strains or lines available

References

• Original: J:238919 Canali S, et al., Endothelial cells produce bone morphogenetic protein 6 required for iron homeostasis in mice. Blood. 2017 Jan 26;129(4):405-414
• All: 2 reference(s)