Gja10tm1.1(icre)Aah
Targeted Allele Detail
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Symbol: |
Gja10tm1.1(icre)Aah |
Name: |
gap junction protein, alpha 10; targeted mutation 1.1, Arlene Hirano |
MGI ID: |
MGI:5908159 |
Synonyms: |
Cx57-iCre |
Gene: |
Gja10 Location: Chr4:32596960-32602760 bp, - strand Genetic Position: Chr4, 14.25 cM
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Alliance: |
Gja10tm1.1(icre)Aah page
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Germline Transmission: |
Earliest citation of germline transmission:
J:240232
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
129S4/SvJae
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Allele Type: |
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Targeted (Recombinase) |
Mutations: |
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Insertion, Intragenic deletion
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Gja10tm1.1(icre)Aah expression driven by
1 gene
Knock-in expression driven by:
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Mutation details: The protein-coding region of the mouse Gja10 gene was replaced with a FRT flanked neo cassette and an in-frame, icre recombinase gene. Subsequent flp mediated recombination removed the neo cassette and brought the cre recombinase under the control of the endogenous gene promoter.
(J:240232)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Gja10
(mouse)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Gja10 Mutation: |
22 strains or lines available
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Original: |
J:240232 Hirano AA, et al., Targeted Deletion of Vesicular GABA Transporter from Retinal Horizontal Cells Eliminates Feedback Modulation of Photoreceptor Calcium Channels. eNeuro. 2016 Mar-Apr;3(2):ENEURO.0148-15.2016 |
All: |
8 reference(s) |
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