Del(1Fcgr2b-Fcgr3)1Jsv
Targeted Allele Detail

Summary

• Symbol: Del(1Fcgr2b-Fcgr3)1Jsv
• Name: deletion, Chr 1, J Sjef Verbeek 1
• MGI ID: MGI:5907363
• Synonyms: Del1Jsv, FcgammaR2/3/4 KO
• Gene: Del(1Fcgr2b-Fcgr3)1Jsv Location: unknown Genetic Position: Chr1, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:264675
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Intergenic deletion, Intragenic deletion
• Del(1Fcgr2b-Fcgr3)1Jsv involves 16 genes/genome features (Fcgr2b, Gm38204, Gm34968 ...) View all
• Mutation details: Cre-mediated recombination between Fcgr2b^tm1.1Sjv and Fcgr3^tm2Sjv results in the partial deletion of each gene and complete deletion of the sequence between them, including Fcgr4. (J:264675)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Del(1Fcgr2b-Fcgr3)1Jsv Mutation: 0 strains or lines available

References

• Original: J:264675 Fransen MF, et al., A Restricted Role for FcgammaR in the Regulation of Adaptive Immunity. J Immunol. 2018 Apr 15;200(8):2615-2626
• All: 7 reference(s)