Rnf180^tm1.1Jaru
Targeted Allele Detail

Summary

• Symbol: Rnf180^tm1.1Jaru
• Name: ring finger protein 180; targeted mutation 1.1, Jun Aruga
• MGI ID: MGI:5903887
• Gene: Rnf180 Location: Chr13:105267075-105431406 bp, - strand Genetic Position: Chr13, 56.92 cM, cytoband D1
• Alliance: Rnf180^tm1.1Jaru page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:199865
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 6, which contains the RING finger domain, was replaced with a loxP-flanked PGK-neo cassette. Cre-mediated recombination removed the PGK-neo cassette. (J:199865)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rnf180 Mutation: 21 strains or lines available

References

• Original: J:199865 Kabayama M, et al., Rines E3 Ubiquitin Ligase Regulates MAO-A Levels and Emotional Responses. J Neurosci. 2013 Aug 7;33(32):12940-53
• All: 1 reference(s)