Dlg5^tm2.1Vv
Targeted Allele Detail

Summary

• Symbol: Dlg5^tm2.1Vv
• Name: discs large MAGUK scaffold protein 5; targeted mutation 2.1, Valeri Vasioukhin
• MGI ID: MGI:5903242
• Gene: Dlg5 Location: Chr14:24184021-24295988 bp, - strand Genetic Position: Chr14, 14.26 cM
• Alliance: Dlg5^tm2.1Vv page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:238700
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A targeting vector containing a FRT-site flanked neo selection cassette was used to insert loxP sites flanking exon 4 (ENSEMBL:ENSMUSE00001373163). Flp-mediated recombination removed the FRT-flanked neo cassette. (J:238700)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Dlg5 Mutation: 126 strains or lines available

References

• Original: J:238700 Kwan J, et al., DLG5 connects cell polarity and Hippo signaling protein networks by linking PAR-1 with MST1/2. Genes Dev. 2016 Dec 15;30(24):2696-2709
• All: 1 reference(s)