Crnde^tm1.1Vlcg
Targeted Allele Detail

Summary

• Symbol: Crnde^tm1.1Vlcg
• Name: colorectal neoplasia differentially expressed, non-protein coding; targeted mutation 1.1, Velocigene
• MGI ID: MGI:5902986
• Gene: Crnde Location: Chr8:93052661-93082739 bp, - strand Genetic Position: Chr8, 44.89 cM, cytoband C5
• Alliance: Crnde^tm1.1Vlcg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101977
• Parent Cell Line: VGF1 (ES Cell)
• Strain of Origin: (129S6/SvEvTac x C57BL/6NTac)F1

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Homologous recombination replaced 25 kb of genomic sequence, containing all exons from exon 2 onwards, with a lacZ reporter cassette (including Kozak sequence and ATG start codon) and a loxP site flanked neomycin resistance gene cassette. Cre-mediated recombination removed the floxed neo cassette. (J:204277)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Crnde Mutation: 0 strains or lines available

Notes

The version of this allele that contains/ does not contain the neomycin selection cassette, Crnde^tm1Vlcg, has been analyzed.

References

• Original: J:204277 Sauvageau M, et al., Multiple knockout mouse models reveal lincRNAs are required for life and brain development. Elife. 2013;2(0):e01749
• All: 2 reference(s)