Tg(Mt1-HGF)1Gvw
Transgene Detail

Summary

• Symbol: Tg(Mt1-HGF)1Gvw
• Name: transgene insertion 1, George F Vande Woude
• MGI ID: MGI:5829717
• Synonyms: hHGF-Tg
• Transgene: Tg(Mt1-HGF)1Gvw Location: unknown
• Alliance: Tg(Mt1-HGF)1Gvw page

Transgene origin

• Strain of Origin: C3H or C57BL/6

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(Mt1-HGF)1Gvw expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  HGF (3082)

  Hgf	(MGI:96079)

• Tg(Mt1-HGF)1Gvw expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Mt1 (MGI:97171)

• Mutation details: The transgenic construct consists of mouse metallothionein I promoter sequences (Mt1) placed upstream of a cDNA sequence encoding the human hepatocyte growth factor. (J:239806)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:239806 Zhang YW, et al., Enhanced growth of human met-expressing xenografts in a new strain of immunocompromised mice transgenic for human hepatocyte growth factor/scatter factor. Oncogene. 2005 Jan 06;24(1):101-6
• All: 3 reference(s)